Humans are living longer than ever-but even today, some of us will make it in the past by 100. Even very few people will reach 110 or 115. In fact, in the world, less than 250 of them are “Super Sentin”-AKA people over 110 people-and only three of them are 115 pluses.
They are a rare breed, the point. But Why?? What does these super -exagns set to those of us besides the rest of us? Is it nature, or upbringing? A new analysis has not yet been reviewed, maybe some indicators can be found-and this is all thanks to a remarkable woman.
An extremely Sunni year’s biology
Born on March 4, 1907, Maria Bernity Morira “was the oldest certified person in the world since January 2023 until she reached the age of 117 and 168 days on August 19, 2024.” “In Catalonia, the historical nation where [Branyas Morera] Living, the age of women is expected to be 86 years old, so she exceeded the average limit of over 30 years.
Where most of us will see an amazing feat of longevity, or perhaps a living relationship with a lost past, researchers behind the paper saw a rare opportunity to collect data.
In paper reports, when Bernity Morira was clearly 116 years old and 74 days old, using the samples collected, researchers “in various tissues developed its genomic, transcromer, metabolomic, proteomic, microbial and epigonomic landscapes. Compared, some of which at the age of 25, to see what Brania is different for Morira.
What they got was amazing. The Brania Morra was not much more marker associated with the age of the Morrar – but in some cases, he was “the youngest” of all the patterns. Take the length of the telomer, for example: hats at the end of the chromosome usually appear to decrease in length with our age – but at the age of 116, the telomeris of Brenus Morira also had the largest length of articles in the 30s.
The team has found genetic forms that are known for preventing diseases such as cardiovascular disorders, diabetes, and neurodegery. These three There are some important reasons for death in developed countries like the United States. And when he used various epigentic “watches” to calculate the biological period of DNA methyllation -based Brania Morrrrrrrrrrrrrrrrrrrrrrrrrr.[U]Sing six different epaginic watches […] According to the team, all the algorithms based on DNA methanellation yielded the same result. “The team reported.” Our superstites exhibited the old biological age far more than the age of its original history, and this happened in three different tissues. “
It was not true for control patterns – there, as expected, the biological age almost stands with the real ages of the subjects. But when the team double checked with another, fully irrelevant type of examination, they have the same result-it is suggested that “one of the reasons is that our supernimars have reached such a world record age that its cells ‘felt’ or ‘behaved’ or ‘behaved’ like young cells.
Overall, how unique the Biranas Morira’s biology was really – but it is difficult for it Really Hammer Home: When the team compared its genome to the control seat of 75 women from the same area, they found seven rare “extreme” variations that were not present. Anyone Other articles.
Researchers suggested that “these variations can be unique to it, and can contribute to an extraordinary longevity.”
Lessons of age
At the top of the Branias Morira’s incredibly fortunate genetic makeup, there were some factors that combined a doll of “upbringing” in “nature”. The team noted, and mostly got stuck in the Mediterranean-style diet-fling, as it spent his entire life on the coast of this particular sea. These habits have potentially played a vital role in its highly healthy gut biome and cholesterol levels – though researchers have received abundance of genetic variations and naturally effective lipid metabolism, which has potentially helped the latter.
Then there were James. It may seem clutch, but in some ways it is true: you are just as old as you feel – and Brania Morira felt very young. “Despite many emotional traumatic events during the last years of his life, like his son’s death, he maintained a strong physical and mental health throughout his life with good sleep habits. […] And active social life, “researchers wrote.” She enjoyed the mass […] Standard time with family and friends, playing with dogs, reading books, increasing the garden, walking, and playing piano.
It will live all activity and healthy life What is the potential to cooperate For his longevity – and these extra years kept even more pleasant. To be mentally dynamic Help help Academic malfunction and dementia, as can be social. In the meantime to be physically vibrant, Can help you Be free and physically capable for longer. And of course, the two talk together: Exercise is good for your brain health, and – well, it’s difficult to grieve when you are playing with a paper.
How to live the 100 of the past
So, those of us who are hoping will make a copy of it in a few decades, what was the key to the long life of Brania Morira? I Her own wordsIt was his “organized life and a pleasant environment” – but if you ask scientists, it was much more complicated.
He concluded, “Our results suggest that extremely human longevity can be the characteristic of two separate and potentially irrelevant sets of features within the same individual.” “On the one hand, there are very advanced age -featured bio -markers, such as shortened telomeris, mutation associated with clonal hematoposis, or the old B cell population.
“All these results make it clear that aging and illness, under certain conditions, challenging the general impression that they are linked to how they are connected.”
In basic English: Bernity Morrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrrresors were very lucky, in ways that we would probably not fully understand for a while. But he also benefited the most of this fortune, he took care of himself till the end, well -eaten, stay active, and walk with his friends and family. We should all be very lucky.
Can be read on pre -print Borexiao server.
